Projects of limited time and scope that do not meet these characteristics of innovative, ground-breaking research should consider applying for a small Research Project Grant (Parent R01). Reviewers will assess whether materials or procedures proposed are potentially hazardous to research personnel and/or the environment, and if needed, determine whether adequate protection is proposed. Is there a plan to obtain required study agent(s)? Email:support@grants.gov, Sailaja Koduri, Ph.D.National Institute of General Medical Sciences (NIGMS)Email: sailaja.koduri@nih.gov, Maqsood Wani, Ph.D.Center for Scientific Review (CSR)Email: wanimaqs@csr.nih.gov, Lisa MoellerNational Institute of General Medical Sciences (NIGMS)Email: moellerl@mail.nih.gov. New investigators are encouraged to apply for an R01 (see NOT-OD-09-013, "Revised New and Early Stage Investigator Policies) or an R03 (see NIAMS Small Grant Program for New Investigators). 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Publication plan that enumerates planned manuscripts and proposed lead authorship. Review of Applications: WebRT @metinuz_PhD: I am thrilled to announce that I have been awarded a new @NIDDKgov /@NIH Stephen I. Katz Early-Stage Investigator Research Project Grant-R01 providing ", 6. Applications should include a letter signed by the Institutional Business Official certifying PI's eligibility for the supplement award. Entering $0 does not imply that the PD/PI will not receive any salary or fringe benefit support from the grant. Supplements to MIRAs: MIRAs will be eligible for Research Supplements to Promote Diversity in Health-Related Research , for Research Supplement to Promote Re-Entry into Biomedical and Behavioral Research Careers , and for Administrative Supplements for Equipment Purchases . Is a refinement, improvement, or new application of theoretical concepts, approaches or methodologies, instrumentation, or interventions proposed? If this letter is not included, the application will be considered incomplete and will not be reviewed.This information could include start-up packages and other institutional research support, space available to the PD/PI, salary support commitment for the PD/PI, skills and career development opportunities for the PD/PI, mentoring during the promotion and tenure process, and career advancement prospects for non-tenure track applicants. These costs may be reimbursed only to the extent considered allowable pre-award costs. Have the methods for standardization of procedures for data management to assess the effect of the intervention and quality control been addressed? NIAMS High Innovation Exploratory/Developmental Research Grant Program. A final RPPR, invention statement, and the expenditure data portion of the Federal Financial Report are required for closeout of an award, as described in the NIH Grants Policy Statement. Relevance of the proposed research to NIGMS priorities. Although only UH2 awardees are generally eligible to apply for UH3 support, specific program initiatives may establish eligibility criteria under which applications could be accepted from applicants demonstrating progress equivalent to that expected under UH2. This NOFO does not allow resubmissions, although a new application can be submitted after an unsuccessful attempt as long as the PD/PI remains eligible, as defined above. For individuals identified as NIs, the software will calculate the ten-year window of Early Stage Investigator (ESI) status based on the date of the terminal research degree or the residency end date entered in the investigators Profile. A description of any additional funds available to ensure sustained research and the availability of carryover funds from previous years and any local assistance, including matching funds or specified 'in kind' support. Appendix: Only limited Appendix materials are allowed. The mission of the National Institute of Arthritis and Musculoskeletal and Skin Diseases is to support research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases; the training of basic and clinical scientists to carry out this research; and the dissemination of information on research progress in these diseases. Please turn on JavaScript and try again. NIAMS strongly encourages the PI of the parent research grant to contact both the scientific contact listed in this table and the NIAMS Program Officer of that grant. NIAMS strongly recommends applicants submit an X02 pre-application.Duration: up to 2 years for the R61 Phase and 1 year for the R33 PhaseBudget Cap: $250,000 direct costs per yearApplications Due: By RFA only, Applicant Information Webinar for NIAMS Research Innovations for Scientific Knowledge (RISK) (X02, R61/R33), FAQsNIAMS Research Innovations for Scientific Knowledge (RISK) (X02, R61/R33), Active Resource-based P30 funding opportunities, Provides critical research infrastructure, shared facilities, services, and resources to groups of investigators, with the broad overall goal of accelerating, enriching, and enhancing the effectiveness of ongoing basic, translational, and clinical research and promoting new research within the NIAMS mission. ESI: NIH defines early stage investigators (ESIs) as new PIs who are within 10 years of having received their Ph.D. degree or completing medical residency (or the equivalent), and have not yet received R01-equivalent grant support (i.e., R01, R35, R37, DP1, DP2, U01 or SC1 grant awards). Content and Form of Application Submission. Provide complete justification using the Budget Justification. Addition of a foreign component requires NIGMS' prior approval. At least 6 months of support must be remaining on the grant at the start of the supplement award. Budget details for mentored candidates in the NIH intramural program will be negotiated with the sponsoring laboratory and will be consistent with offers to scientists in comparable positions. Date 06/2024. In assessing the effectiveness of research project grant investments, NIGMS may use information from progress reports and public databases, PD/PIs, and from participants themselves. The NoA signed by the grants management officer is the authorizing document and will be sent via email to the recipient's business official. Refer to NIH's Early Stage Investigator policies for information about what awards impact ESI status. Each fiscal year (FY), NIAID sets initial paylines conservatively and sets final paylines later. Other supplements offered by NIGMS may also be made available to MIRA recipients, depending on the intention and constraints of the particular supplement program.". Investigators with K awards from another NIH institute may receive an NIGMS MIRA but will be required to adjust their person-months effort on those awards to be smaller than the person-months effort committed to MIRA. is experiencing a serious personal health issue or illness and/or debilitating condition. Recipients must comply with any funding restrictions described in Section IV.6. List ongoing and completed research projects with funding sources from the past three years, and briefly indicate the overall goals of the projects and your responsibilities. Is the process for obtaining informed consent or assent appropriate? For additional information on review of the Vertebrate Animals section, please refer to the Worksheet for Review of the Vertebrate Animals Section. If the goals of the research are achieved, how will scientific knowledge, technical capability, and/or clinical practice be improved? For example, a program that by its nature is not innovative may be essential to advance a field. Progress to date. Applicants are required to follow the instructions for post-submission materials, as described in the policy. Note: NIH will consider a request to extend the period of your ESI status if there has been a lapse in your post-degree training. A description of how the supplement funds will be used to offset the impact to the research program as a result of the critical life event. The recipient must also make semiannual disclosures regarding such proceedings. It is critical that applicants follow the instructions in the Research (R) Instructions in theSF424 (R&R) Application Guideexcept where instructed in this notice of funding opportunity to do otherwise. Are the planned recruitment timelines feasible and is the plan to monitor accrual adequate? NIMHD Financial Management Plan for Grant Awards Follow all instructions for the Appendix as described in the SF424 (R&R) Application Guide. WebMAILING ADDRESS: Office of State Inspector General | P.O. Funding Trends & Support of Guiding Principles - NIDDK List the individuals/organizations with whom consortium or contractual arrangements have been made and indicate whether the collaborating institution is foreign or domestic. Only one award per eligible investigator may be considered for this special payline. Research involving human subjects is permitted in the MIRA program. This FOA will not support core centers (or activities within centers) focused on the generation of biological or genetic data or the development of novel technologies for such generation.Duration: 5 yearsBudget Cap: $500,000 direct costsFAQS: NIAMS Core Centers for Clinical Research (CCCR) - FAQsContact: NIAMS Centers Program, To promote translational research through a multidisciplinary approach on a disease specific theme. But perhaps most noteworthy were his strong commitment to mentorship, his unbridled enthusiasm, and his willingness to devote significant amounts of his time to guiding junior scientists. The total research effort should be determined in person-months and should not include time expended toward teaching, administration not directly related to the PD's/PI's research, and/or clinical duties. The NIAMS funds the following types of grants: Research Grants Research Project Grants (R) Research Programs and Centers (P) Research-Related Programs (S) Supplement Programs Training and Career Development Grants Fellowship Programs (F) Peer Review For both New Investigator (NI) and Early Stage Investigator (ESI) applications, peer reviewers are instructed to focus more on the proposed approach than on the track record, and to expect less preliminary data than would be provided by established investigators. Frequently Asked Questions for the NHLBI Clinical Ancillary Studies FOA Will the program benefit from unique features of the scientific environment, subject populations, or collaborative arrangements? Family-Friendly / Life Events Supplements, NOT-OD-23-031 - Notice of Special Interest: Administrative Supplements to Promote Research Continuity and Retention of NIH Mentored Career Development (K) Award Recipients and Scholars, NOT-OD-023-032 - Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards. Recently issued trans-NIH policy notices may affect your application submission. For Early Stage Investigator MIRA applications it is okay to have a similar ReWARD application under review at the same time, but only one application will be funded. PDs/PIs who are currentlyNew Investigatorsproposing research within the scientific mission of NIGMS are not eligible for this NOFO and should apply instead through PAR-22-180or its subsequent reissuance. In Section H: Indirect Costs, enter your institutional "indirect cost type," "indirect cost rate," "indirect cost base" and "funds requested.". An applicant, at its option, may review information in the designated integrity and performance systems accessible through FAPIIS and comment on any information about itself that a federal agency previously entered and is currently in FAPIIS. Form Approved OMB# 0925-0648 Exp. Participation can give you insights that are likely to improve your ability to compete for a research grant. In carrying out stewardship of grant programs, NIGMS will periodically evaluate the MIRA program, employing the representative measures identified below. Given the methods used to assign participants and deliver interventions, is the study design adequately powered to answer the research question(s), test the proposed hypothesis/hypotheses, and provide interpretable results? Assignment to a Scientific Review Group will be shown in the eRA Commons. Reviewers may expect ESIR01 investigators to have fewer preliminary data and publications than more established researchers do. For these terms of award, see the NIH Grants Policy Statement Part II: Terms and Conditions of NIH Grant Awards, Subpart A: Generaland Part II: Terms and Conditions of NIH Grant Awards, Subpart B: Terms and Conditions for Specific Types of Grants, Recipients, and Activities, including of note, but not limited to: If a recipient is successful and receives a Notice of Award, in accepting the award, the recipient agrees that any activities under the award are subject to all provisions currently in effect or implemented during the period of the award, other Department regulations and policies in effect at the time of the award, and applicable statutory provisions. All page limitations described in the SF424 Application Guide and the Table of Page Limits must be followed. Engagement from different types of institutions and organizations (e.g., research-intensive, undergraduate-focused, minority-serving, community-based). Reviewers will provide an overall impact score to reflect their assessment of the likelihood for the research program to exert a sustained, powerful influence on the research field(s) involved, in consideration of the following review criteria and additional review criteria (as applicable for the program proposed). Investigators Research Strategy: MIRA applications should not use the typical Research Strategy headings of Significance, Innovation, and Approach. Note that the goals of the program of research supported by the MIRA are broader than the specific aims of a single project and should be appropriately described. Do not include annual inflationary increases. Any individual with the skills, knowledge, and resources necessary to carry out the proposed research as the PD/PI is invited to work with their organization to develop an application for support. For more information, see https://grants.nih.gov/policy/clinical-trials/reporting/index.htm. See Section III of this NOFO for information on registration requirements. Pinterest Will creative strategies be employed as needed and appropriate to address the research questions posed? Administrative supplements must support the scope of the original project and provide support during the period of critical life event. Department of Health and Human Services partners. Supplements may not be awarded on the grant that is in a No Cost Extension (NCE). Eligibility Information contains information about registration. A committee of NIAMS program and grants management staff will review request submitted to NIAMS. The payline for ESI applications is typically more generous than the regular payline for established investigators (see NIDDK Funding Policy). This should be a description of the key questions or challenges the PD/PI plans to address and the general strategies that might be used to approach them. Of these, 220 were to ESIs. Applications submitted to the NIH in support of the NIH mission are evaluated for scientific and technical merit through the NIH peer review system. NIGMS strongly encourages potential applicants to confer with the program officer managing awards in their specific research area at least 6 weeks prior to submission for advice on the suitability of the proposed research for NIGMS. Reviewers will consider each of the review criteria below in the determination of scientific merit, however, individual review criterion scores will not be assigned. When feasible, new and early-stage investigator applications are not interspersed with those of established investigators at the review meeting and rather reviewed together as a block. To make available to institutions with a high concentration of NIH extramural research awards, research instruments which will be used on a shared basis. For additional guidance regarding how the provisions apply to NIH grant programs, please contact the Scientific/Research Contact that is identified in Section VII under Agency Contacts of this NOFO. Grants supporting resources for the research community (e.g., R24); Collaborative Program Grant for Multidisciplinary Teams grants**; Biomedical Technology Optimization and Dissemination Center (BTOD) grants***; Grants supporting training, workforce development, or diversity building; Public/State Controlled Institutions of Higher Education, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education), Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education), For-Profit Organizations (Other than Small Businesses), Indian/Native American Tribal Governments (Federally Recognized), Indian/Native American Tribal Governments (Other than Federally Recognized), Eligible Agencies of the Federal Government, Public Housing Authorities/Indian Housing Authorities, Native American Tribal Organizations (other than Federally recognized tribal governments), Faith-based or Community-based Organizations. The research strategy should address the requirements of the NIH policy on rigor in research as well asrequirements related to sex as a biological variable as detailed in the SF424 (R&R) Application Guide.. Candidates must be clinician-scientists working in a research environment, conducting patient-oriented research. PD/PIs are encouraged to contact the scientific contact listed in this NOFO to discuss this option. Obtaining an eRA Commons account can take up to 2 weeks. ESIs are new investigators who are within 10 years of completing either their terminal research degree or their medical residency (whichever is later) at the time they apply for R01 grants. The institution and PD/PI are aware of and accept that other NIGMS research awards, except as allowed in Section I, must be relinquished, and pending NIGMS research applications withdrawn, as a condition of receiving a MIRA. All budget information should be provided on the R&R Budget form for Budget Type Project.. R01 is the activity code for the NIH Research Project Grant program that supports a discrete project that is related to the programmatic interests of one or more of the participating NIH institutes and centers based on their scientific missions. or Ph.D. or equivalent.Duration: Up to 3 yearsCommitment: Full-time research fellowshipProvisions:NRSA Stipends, Tuition/Fees, and Institutional AllowanceApplications Due: Standard dates. Funding Outcomes Data FY16 | National Institute of Neurological Get the latest scientific news and resources on diseases of the bones, joints, muscles, and skin from the NIAMS. Data from The National Science Foundation (NSF) demonstrates that Investigators, especially women, are more likely to cite family responsibilities as a reason for leaving the work force. For the purpose of the STAR Program, NIAMS defines these investigators as those who have successfully renewed a first NIAMS-supported R01 which was received no earlier than 2009 with Early Stage Investigator (ESI) status. If proposed, are the administrative, data coordinating, enrollment and laboratory/testing centers, appropriate for the trial proposed? state the statute or rule or regulation found to have been violated and which resulted in the suspension or revocation: 2. state the penalty imposed for the violation; and. The following section supplements the instructions found in the SF424 (R&R) Application Guide and should be used for preparing an application to this NOFO. Generally, summary statements will be available no later than 30 days before Council. The objective of the program is to facilitate research independence earlier in an investigator's career. See additional ESI extension online help and a video tutorial for further information. Research Strategy (6-page limit) to include: 2. Other Attachments). All recipients of applicable NIH grants and cooperative agreementsare required to report to the Federal Subaward Reporting System (FSRS) available at www.fsrs.gov on all subawards over the threshold. WebThe Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project in an area of science that represents a change in research direction for an early Use the Budget Justification to provide the additional information requested in each budget category identified above only. Has the PD/PI shown evidence of being creative and adaptable, able to recognize new opportunities and to explore new areas of scientific inquiry, and openness to the use of new systems and strategies, as appropriate for the proposed research program?